Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373325 | 0.95 | MTNR1A (0.52) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10640944 | 0.89 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL2227533 | 0.82 | HDAC3 (0.50) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL27396041 | 0.81 | APLNR (0.51) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL20303832 | 0.80 | L3MBTL1 (0.67) | MEN1KMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL17185001 | 0.80 | ACHE (0.49) | ACHEKDM4EALDH1A1HDAC1HDAC6 | |
| SCHEMBL22993631 | 0.80 | ACHE (0.48) | ACHEKMT2AALDH1A1HDAC6MTNR1A | |
| SCHEMBL17184827 | 0.80 | KDM4E (0.50) | ACHEKDM4EKMT2AHDAC6ADRA1D | |
| SCHEMBL8373324 | 0.79 | MTNR1A (0.50) | KDM4EMEN1KMT2AALDH1A1MTNR1A | |
| SCHEMBL3459387 | 0.79 | L3MBTL1 (0.64) | MEN1KMT2AALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101090902-B | Cgrp receptor antagonists | MERCK SHARP & DOHME | 2013-05-29 | — | — | CN | disclosed |