Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789943 | 0.91 | AKT1 (0.36) | CNR2CTSCPROKR1CYP3A4 | |
| SCHEMBL2789481 | 0.88 | PARP1 (0.37) | CNR2CTSC | |
| SCHEMBL2791483 | 0.87 | CNR2 (0.33) | CNR2CTSCPDE3BPDE3ADPP4 | |
| SCHEMBL2789230 | 0.86 | CNR2 (0.39) | CNR2PROKR1DPP4DPP7CYP3A4 | |
| SCHEMBL741160 | 0.84 | BTK (0.31) | CTSCPDE3BPDE3ADPP4 | |
| SCHEMBL741161 | 0.84 | BTK (0.31) | CTSCPDE3BPDE3ADPP4 | |
| SCHEMBL742244 | 0.83 | CFD (0.34) | CTSCDPP4 | |
| SCHEMBL742245 | 0.83 | CFD (0.34) | CTSCDPP4 | |
| SCHEMBL2790507 | 0.83 | CNR2 (0.40) | CNR2PROKR1DPP4DPP7CYP3A4 | |
| SCHEMBL2791698 | 0.82 | PROKR1 (0.37) | CNR2PROKR1DPP4CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |