Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 2/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741160 | 1.00 | BTK (0.31) | BTKALDH1A1TSHRKMT2ANPY1R | |
| SCHEMBL742244 | 0.93 | CFD (0.34) | CTSCCFDDPP4 | |
| SCHEMBL742245 | 0.93 | CFD (0.34) | CTSCCFDDPP4 | |
| SCHEMBL741966 | 0.91 | AKT1 (0.36) | BTKNPY1RCFD | |
| SCHEMBL742052 | 0.91 | AKT1 (0.36) | BTKNPY1RCFD | |
| SCHEMBL742029 | 0.89 | NSD2 (0.36) | CTSC | |
| SCHEMBL742030 | 0.89 | NSD2 (0.36) | CTSC | |
| SCHEMBL739855 | 0.85 | PIK3CD (0.37) | BTKCTSC | |
| SCHEMBL739856 | 0.85 | PIK3CD (0.37) | BTKCTSC | |
| SCHEMBL2791483 | 0.85 | CNR2 (0.33) | CTSCCFDDPP4PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | claimed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |