Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300273 | 0.86 | ALDH1A1 (0.47) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28792827 | 0.81 | PTPN1 (0.54) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10486563 | 0.81 | ALOX15 (0.70) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28576970 | 0.79 | ALOX15 (0.60) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30903607 | 0.79 | ALOX15 (0.60) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8876175 | 0.78 | ALOX15 (0.58) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8876237 | 0.78 | ALOX15 (0.55) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| Isoflavone SCHEMBL8028 | 0.78 | ALDH1A1 (0.66) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| Isoflavone SCHEMBL6290885 | 0.78 | ALDH1A1 (0.66) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E | |
| Isoflavone SCHEMBL31264756 | 0.78 | ALDH1A1 (0.66) | ALOX15ALOX12ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102260256-B | Diaryl pyrazolo [3,4-b] pyridine heterocyclic compound as well as preparation method and drug application | UNIV SHAANXI NORMAL | 2013-06-12 | — | — | CN | claimed |