Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576970 | 1.00 | ALOX15 (0.60) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11705295 | 0.87 | PDCD1 (0.49) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10486563 | 0.83 | ALOX15 (0.70) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8876175 | 0.80 | ALOX15 (0.58) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27924239 | 0.79 | ALOX15 (0.57) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27555045 | 0.79 | ALOX15 (0.57) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8876811 | 0.78 | ALOX15 (0.56) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL18235035 | 0.78 | MAOB (0.44) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8876237 | 0.77 | ALOX15 (0.55) | ALOX15ALOX12ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11191895 | 0.77 | TDP1 (0.50) | ALOX15ALOX12KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185486-B | Antitumor agent 3-aryl-4H-chromen-4-one for the treatment of cancer | 肯塔基大学研究基金会 | 2024-05-10 | — | — | CN | disclosed |