Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | USP7 | Q93009 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | PRF1 | P14222 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502688 | 0.87 | SCN9A (0.54) | SCN9AHIF1ACNR2SIRT6GSK3B | |
| SCHEMBL4780143 | 0.85 | EGLN1 (0.56) | USP7EGLN1MAP4K4HIF1ACNR2 | |
| SCHEMBL20294380 | 0.83 | KCNA5 (0.47) | SCN9AMAP4K4HIF1ASIRT6CHEK2 | |
| SCHEMBL4501855 | 0.81 | MARS1 (0.52) | MAP4K4PRF1 | |
| SCHEMBL27945020 | 0.81 | USP7 (0.47) | SCN9AUSP7EGLN1MAP4K4HIF1A | |
| SCHEMBL4768283 | 0.80 | KMT2A (0.57) | EGLN1MAP4K4SIRT6GSK3BKMT2A | |
| SCHEMBL4280915 | 0.80 | SIRT6 (0.41) | EGLN1MAP4K4HIF1ASIRT6CHEK2 | |
| SCHEMBL27772735 | 0.80 | MAPK1 (0.53) | USP7EGLN1HIF1ADEGS1KMT2A | |
| SCHEMBL2927582 | 0.79 | HIF1A (0.53) | HIF1ACHEK2GSK3BKMT2A | |
| SCHEMBL7698312 | 0.78 | NOS3 (0.43) | GSK3BKMT2APRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429583-A | Triazole derivatives as WNT signaling pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF | 2013-12-04 | — | — | CN | disclosed |