Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945701 | 0.83 | HRH4 (0.64) | KDM4ENCF1ALDH1A1HRH4POLB | |
| SCHEMBL11275047 | 0.80 | NCF1 (0.58) | KDM4EMAPTNCF1ALDH1A1HPGD | |
| SCHEMBL12701330 | 0.75 | PTK2 (0.50) | KDM4EMAPTALDH1A1HPGDPIK3CA | |
| SCHEMBL2726482 | 0.72 | HRH4 (0.50) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL11272318 | 0.70 | KDM4E (0.59) | KDM4EMAPTNCF1ALDH1A1HPGD | |
| SCHEMBL12701060 | 0.70 | KDM4E (0.54) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL11283343 | 0.69 | NCF1 (0.50) | KDM4EMAPTNCF1ALDH1A1HPGD | |
| SCHEMBL29639090 | 0.69 | HTR6 (0.51) | KDM4EMAPTNCF1ALDH1A1HPGD | |
| SCHEMBL17942737 | 0.69 | ALDH1A1 (0.67) | KDM4EMAPTNCF1ALDH1A1HPGD | |
| SCHEMBL11739114 | 0.68 | KDM4E (0.69) | KDM4EMAPTNCF1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373971-A | Urea compounds as protein kinase inhibitors | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-10-30 | — | — | CN | disclosed |