Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851849 | 0.83 | ALDH1A1 (0.38) | OPRM1OPRD1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1656971 | 0.82 | HDAC4 (0.43) | OPRM1OPRD1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL670971 | 0.78 | OPRM1 (0.56) | OPRM1OPRD1NPSR1SLC6A4SLC22A1 | |
| SCHEMBL29539902 | 0.76 | HDAC4 (0.48) | OPRM1OPRD1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28790841 | 0.76 | HDAC4 (0.51) | OPRM1OPRD1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL22721906 | 0.76 | HDAC4 (0.48) | OPRM1OPRD1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL27868888 | 0.76 | OPRM1 (0.41) | OPRM1OPRD1ALDH1A1SLC6A4SLC6A2 | |
| SCHEMBL1599327 | 0.73 | LMNA (0.44) | OPRM1OPRD1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL4506478 | 0.73 | OPRM1 (0.53) | OPRM1OPRD1ALDH1A1NPSR1HDAC4 | |
| SCHEMBL27851848 | 0.72 | MAPT (0.39) | ALDH1A1SMN1; SMN2SLC6A3L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201262-A | Autotaxin inhibitors and uses thereof | AMIRA PHARMACEUTICALS INC | 2013-07-10 | — | — | CN | disclosed |