SCHEMBL2793178

SCHEMBL2793178

CC(C)(C)OC(=O)N1CCC(CCl)(NC(=O)OCc2ccccc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.47
OPRK1 P41145 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TACR1 P25103 1/20 0.45
BACE1 P56817 1/20 0.45
STS P08842 1/20 0.44
P2RX7 Q99572 6/20 0.44
YAP1 P46937 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
ATM Q13315 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607180 0.90 MEN1 (0.46) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL6083618 0.89 EGLN2 (0.50) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL605683 0.89 MEN1 (0.46) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL17609000 0.89 OPRD1 (0.47) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL607947 0.89 TACR1 (0.47) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL16825735 0.88 MEN1 (0.45) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL16825914 0.87 OPRD1 (0.45) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL24940830 0.86 MEN1 (0.43) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL17608882 0.86 P2RX7 (0.44) OPRD1OPRK1MEN1KMT2ATACR1
SCHEMBL551650 0.86 MEN1 (0.48) OPRD1OPRK1MEN1KMT2ATACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100168421-A1 A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2010-07-01 US disclosed
EP-2164829-A1 A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2010-03-24 EP disclosed
WO-2008150089-A1 A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF ILDONG PHARMACEUTICAL CO., LTD. (KR) 2008-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168421-A1 A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF PDF, PEPD, DPEP1 OPRD1 4455/4885OPRK1 4651/4885MEN1 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.