Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793374 | 1.00 | ADRB2 (0.39) | ADRB2ADRB1SIGMAR1CHRM2ADRB3 | |
| SCHEMBL2793875 | 0.93 | ADRB2 (0.36) | ADRB2ADRB1ADRB3DRD3CHRM3 | |
| SCHEMBL2795758 | 0.90 | ADRB2 (0.40) | ADRB2ADRB1SIGMAR1CHRM2ADRB3 | |
| SCHEMBL2795756 | 0.90 | ADRB2 (0.40) | ADRB2ADRB1SIGMAR1CHRM2ADRB3 | |
| SCHEMBL2794968 | 0.87 | ADRB2 (0.53) | ADRB2ADRB1 | |
| SCHEMBL2794965 | 0.87 | ADRB2 (0.53) | ADRB2ADRB1 | |
| SCHEMBL6254124 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL6254119 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL2827190 | 0.85 | ADRB2 (0.43) | ADRB2ADRB1CHRM2ADRB3DRD2 | |
| SCHEMBL2847126 | 0.85 | ADRB2 (0.43) | ADRB2ADRB1CHRM2ADRB3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057122-B1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE 2 ADRENERGIC RECEPTOR | ALMIRALL SA (ES) | 2010-09-01 | — | — | EP | disclosed |
| US-20100168161-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168161-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ADRB2, ADRB1, ADRA2C | ADRB2 1/4885ADRB1 2/4885SIGMAR1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.