SCHEMBL27934848

SCHEMBL27934848

Clc1cc(Cc2ccccc2)cc(Cc2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.60
MEN1 O00255 1/20 0.48
CYP3A4 P08684 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
KMT2A Q03164 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
IDH1 O75874 1/20 0.45
SIGMAR1 Q99720 1/20 0.44
PNMT P11086 1/20 0.43
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
ALDH1A1 P00352 1/20 0.42
SLC22A2 O15244 1/20 0.42
LTA4H P09960 1/20 0.41
PGR P06401 1/20 0.41
TSHR P16473 1/20 0.41
TAAR1 Q96RJ0 2/20 0.41
PTPN2 P17706 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16770503 0.95 CALM1 (0.60) CALM1MEN1CYP3A4HPGDALOX15
Hydrogen Sulfide SCHEMBL28232332 0.93 CALM1 (0.57) CALM1MEN1CYP3A4HPGDALOX15
SCHEMBL28173954 0.87 CALM1 (0.80) CALM1IDH1BCL2BCL2L1ALDH1A1
SCHEMBL4928597 0.85 MEN1 (0.50) CALM1MEN1CYP3A4HPGDALOX15
SCHEMBL3301781 0.83 PNMT (0.58) CALM1MEN1CYP3A4HPGDALOX15
Ammonia Solution, Strong SCHEMBL18010559 0.81 PNMT (0.56) CALM1MEN1CYP3A4HPGDALOX15
SCHEMBL23487472 0.80 MAOA (0.46) HPGDALOX15HSD17B10SIGMAR1PNMT
SCHEMBL196969 0.79 CALM1 (0.67) CALM1MEN1CYP3A4HPGDALOX15
SCHEMBL13971231 0.78 CALM1 (0.75) CALM1IDH1BCL2BCL2L1LTA4H
SCHEMBL7613502 0.78 CALM1 (0.75) CALM1IDH1BCL2BCL2L1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459405-B Process for producing transition metal complex, catalyst for trimerization, process for producing 1-hexene, process for producing substituted cyclopentadiene compound (1) 住友化学株式会社 2016-09-28 CN disclosed
CN-103459405-A Process for producing transition metal complex, catalyst for trimerization, process for producing 1-hexene, process for producing substituted cyclopentadiene compound SUMITOMO CHEMICAL CO 2013-12-18 CN disclosed