Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275331 | 0.81 | CES1 (0.36) | KDM4EMEN1MAPTKMT2ANOTUM | |
| SCHEMBL8529795 | 0.76 | DRD2 (0.52) | MEN1MAPTKMT2ANOTUMHTR2C | |
| SCHEMBL3873979 | 0.73 | KDM4E (0.42) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL11015073 | 0.73 | MAPT (0.44) | KDM4EMEN1MAPTKMT2ANOTUM | |
| SCHEMBL8089058 | 0.73 | KDM4E (0.48) | KDM4EMEN1MAPTKMT2ANOTUM | |
| SCHEMBL27435131 | 0.71 | ALDH1A1 (0.52) | KDM4EMAPTGAAHTR2CAHR | |
| SCHEMBL9538393 | 0.70 | MEN1 (0.58) | KDM4EMEN1MAPTKMT2ANOTUM | |
| SCHEMBL5758073 | 0.69 | KDM4E (0.39) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL10840667 | 0.69 | AR (0.43) | HTR2CCHRNB2CHRNA4HTR2A | |
| SCHEMBL8526795 | 0.65 | DRD2 (0.46) | MEN1MAPTKMT2ANOTUMHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103275021-B | N-dichloracetyl-6, 7-dichloro-1, 2, 3, 4-tetrahydro quinoxaline and preparation method thereof | UNIV NORTHEAST AGRICULTURAL | 2015-05-20 | — | — | CN | claimed |
| CN-110483420-B | Preparation method of tetrahydroquinoxaline compound | 云南民族大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-103275021-B | N-dichloracetyl-6, 7-dichloro-1, 2, 3, 4-tetrahydro quinoxaline and preparation method thereof | UNIV NORTHEAST AGRICULTURAL | 2015-05-20 | — | — | CN | disclosed |
| CN-103275021-A | N-dichloracetyl-6, 7-dichloro-1, 2, 3, 4-tetrahydro quinoxaline and preparation method thereof | UNIV NORTHEAST AGRICULTURAL | 2013-09-04 | — | — | CN | disclosed |