Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 6/20 | 0.42 |
| ▸ | BRD2 | P25440 | 2/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704041 | 0.80 | BRD4 (0.39) | HPGDNOTUMBRD4BRD2BRD3 | |
| SCHEMBL27677805 | 0.78 | CRHBP (0.56) | HPGDCRHBPCRHR2LMNAALDH1A1 | |
| SCHEMBL28080836 | 0.75 | F2RL3 (0.39) | NOTUMBRD4BRD2BRD3BRDT | |
| SCHEMBL27855145 | 0.75 | ALDH1A1 (0.30) | LMNAALDH1A1 | |
| SCHEMBL27889164 | 0.74 | ALDH1A1 (0.40) | HPGDNOTUMLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28099985 | 0.73 | PTGDR2 (0.30) | — | |
| SCHEMBL2638817 | 0.72 | NOTUM (0.48) | HPGDNOTUMBRD4CRHBPCRHR2 | |
| SCHEMBL28905120 | 0.71 | GAA (0.41) | TP53LMNAALDH1A1TSHRGAA | |
| SCHEMBL28046385 | 0.71 | BRD4 (0.40) | BRD4BRD2BRD3BRDTLMNA | |
| SCHEMBL28495369 | 0.71 | HPGD (0.57) | HPGDNOTUMBRD4TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274989-B | The preparation method of octahydro cyclopentano [C] pyrrole derivative and salt thereof | NANJING LYNSCI CHEMICAL CO., LTD. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103274989-A | Preparation method of octahydrocyclopenta[C]pyrrole derivatives and salts thereof | NANJING LYNSCI CHEMICAL CO LTD | 2013-09-04 | — | — | CN | disclosed |