Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080903 | 0.92 | ALDH1A1 (0.43) | ADRA1DLMNAALDH1A1 | |
| SCHEMBL28080894 | 0.90 | ALDH1A1 (0.47) | BRD4ADRA1DLMNAALDH1A1 | |
| SCHEMBL28080828 | 0.88 | CCR2 (0.46) | — | |
| SCHEMBL28080843 | 0.88 | CYP11B1 (0.44) | ARLMNAALDH1A1 | |
| SCHEMBL28080966 | 0.88 | GFER (0.46) | MAPK8LMNAALDH1A1 | |
| SCHEMBL28831833 | 0.86 | GPR52 (0.40) | GAAADRA1DMAPK8GPR52ALDH1A1 | |
| SCHEMBL28080891 | 0.85 | ALDH1A1 (0.44) | BRD4ADRA1DLMNAALDH1A1 | |
| SCHEMBL27962502 | 0.85 | HDAC4 (0.37) | TSHRBRD4SERPINE1GPR52 | |
| SCHEMBL28080840 | 0.84 | COMT (0.41) | ADRA1DMAPK8GPR52 | |
| SCHEMBL28831826 | 0.82 | AR (0.41) | ADRA1DARLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804108-B | A kind of method preparing primary amine | 沈阳药科大学 | 2016-08-03 | — | — | CN | disclosed |