Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28483654 | 0.77 | CHRM3 (0.45) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL10524246 | 0.77 | CHRM3 (0.57) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| Fenpipramide SCHEMBL149504 | 0.76 | CHRM2 (0.60) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL219257 | 0.76 | CHRM2 (0.60) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL9295790 | 0.75 | CHRM3 (0.59) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL10392372 | 0.75 | CHRM3 (0.55) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL4153935 | 0.75 | CHRM3 (0.55) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL27963558 | 0.75 | CHRM3 (0.55) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| Fenpipramide SCHEMBL7558279 | 0.75 | CHRM2 (0.59) | CHRM3CHRM2CHRM1KCNH2LMNA | |
| SCHEMBL11714181 | 0.74 | CHRM3 (0.53) | CHRM3CHRM2CHRM1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103274983-A | Pyrrole derivatives and preparation method thereof | ZHU XUEQI | 2013-09-04 | — | — | CN | disclosed |