Fenpipramide

Fenpipramide

SCHEMBL149504

NC(=O)C(CCN1CCCCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 0.60
CYP2D6 P10635 6/20 0.60
CHRM1 P11229 6/20 0.60
OPRM1 P35372 4/20 0.60
KCNH2 Q12809 4/20 0.60
HTR1A P08908 3/20 0.60
LMNA P02545 2/20 0.60
OPRD1 P41143 1/20 0.57
MAPK1 P28482 2/20 0.55
CHRM3 P20309 6/20 0.54
CHRM4 P08173 4/20 0.54
CHRM5 P08912 4/20 0.54
SIGMAR1 Q99720 2/20 0.54
KDM4E B2RXH2 1/20 0.54
DRD2 P14416 1/20 0.54
DRD1 P21728 1/20 0.54
HTR2A P28223 1/20 0.54
DRD3 P35462 1/20 0.54
SCN1A P35498 1/20 0.54
SCN2A Q99250 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219257 1.00 CHRM2 (0.60) CHRM2CYP2D6CHRM1OPRM1KCNH2
Fenpipramide SCHEMBL7558279 0.98 CHRM2 (0.59) CHRM2CYP2D6CHRM1OPRM1KCNH2
Fenpipramide SCHEMBL11716116 0.96 OPRM1 (0.56) CHRM2CYP2D6CHRM1OPRM1KCNH2
Norpipanone SCHEMBL25085 0.87 OPRM1 (0.75) CHRM2CYP2D6CHRM1OPRM1KCNH2
Norpipanone SCHEMBL316886 0.85 OPRM1 (0.73) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL8880422 0.84 CHRM2 (0.47) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL9248078 0.84 KMT2A (0.57) OPRM1HTR1ALMNAOPRD1SIGMAR1
SCHEMBL11722508 0.82 CYP2D6 (0.57) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL10768406 0.81 OPRM1 (0.63) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL1492481 0.81 OPRM1 (0.63) CHRM2CYP2D6CHRM1OPRM1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3711797-A1 AEROSOL DELIVERY DEVICE AND METHOD OF OPERATING THE AEROSOL DELIVERY DEVICE PARI Pharma GmbH (DE) 2020-09-23 EP claimed
US-10744277-B2 Aerosol delivery device and method of operating the aerosol delivery device PARI PHARMA GMBH (DE) 2020-08-18 US claimed
US-20160310681-A1 AEROSOL DELIVERY DEVICE AND METHOD OF OPERATING THE AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2016-10-27 US claimed
EP-3082918-A1 AEROSOL DELIVERY DEVICE AND METHOD OF OPERATING THE AEROSOL DELIVERY DEVICE PARI Pharma GmbH (DE) 2016-10-26 EP claimed
WO-2015091356-A1 AEROSOL DELIVERY DEVICE AND METHOD OF OPERATING THE AEROSOL DELIVERY DEVICE PARI PHARMA GMBH (DE) 2015-06-25 WO claimed
EP-2883564-A1 Aerosol delivery device and method of operating the aerosol delivery device PARI Pharma GmbH (DE) 2015-06-17 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1227856-B1 INHALATION NEBULIZER PARI PHARMA GMBH (DE) 2008-08-13 EP claimed
US-20060054166-A1 Inhalation nebulizer PARI GMBH SPEZIALISTEN FUR EFFEKTIVE INHALATION (DE) 2006-03-16 US claimed
US-6962151-B1 Inhalation nebulizer Pari GmbH Spezialisten für effektive Inhalation (DE) 2005-11-08 US claimed
US-20040247628-A1 Kit for the preparation of a pharmaceutical composition PARI PHARMA GMBH (DE) 2004-12-09 US claimed
EP-1438019-A1 KIT FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION PARI GmbH Spezialisten für effektive Inhalation (DE) 2004-07-21 EP claimed
WO-2003035030-A1 KIT FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION PARI GMBH (DE) 2003-05-01 WO claimed
EP-1227856-A1 INHALATION NEBULIZER PARI GmbH Spezialisten für effektive Inhalation (DE) 2002-08-07 EP claimed
WO-2001034232-A9 INHALATION NEBULIZER PARI GMBH (DE) 2002-08-01 WO claimed
WO-2001034232-A1 INHALATION NEBULIZER Pari GmbH Spezialisten für effektive Inhalation (DE) 2001-05-17 WO claimed
EP-0984974-A1 GLYCOCONJUGATES OF OPIATED SUBSTANCES ROLABO S.L. (ES) 2000-03-15 EP claimed
WO-1998054196-A1 GLYCOCONJUGATES OF OPIATED SUBSTANCES ROLABO SL (ES) 1998-12-03 WO claimed