SCHEMBL219257

SCHEMBL219257

NC(=O)C(CCN1CCCCCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 0.60
CYP2D6 P10635 6/20 0.60
CHRM1 P11229 6/20 0.60
OPRM1 P35372 4/20 0.60
KCNH2 Q12809 4/20 0.60
HTR1A P08908 3/20 0.60
LMNA P02545 2/20 0.60
OPRD1 P41143 1/20 0.57
MAPK1 P28482 2/20 0.55
CHRM3 P20309 6/20 0.54
CHRM4 P08173 4/20 0.54
CHRM5 P08912 4/20 0.54
SIGMAR1 Q99720 2/20 0.54
KDM4E B2RXH2 1/20 0.54
DRD2 P14416 1/20 0.54
DRD1 P21728 1/20 0.54
HTR2A P28223 1/20 0.54
DRD3 P35462 1/20 0.54
SCN1A P35498 1/20 0.54
SCN2A Q99250 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenpipramide SCHEMBL149504 1.00 CHRM2 (0.60) CHRM2CYP2D6CHRM1OPRM1KCNH2
Fenpipramide SCHEMBL7558279 0.98 CHRM2 (0.59) CHRM2CYP2D6CHRM1OPRM1KCNH2
Fenpipramide SCHEMBL11716116 0.96 OPRM1 (0.56) CHRM2CYP2D6CHRM1OPRM1KCNH2
Norpipanone SCHEMBL25085 0.87 OPRM1 (0.75) CHRM2CYP2D6CHRM1OPRM1KCNH2
Norpipanone SCHEMBL316886 0.85 OPRM1 (0.73) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL8880422 0.84 CHRM2 (0.47) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL9248078 0.84 KMT2A (0.57) OPRM1HTR1ALMNAOPRD1SIGMAR1
SCHEMBL11722508 0.82 CYP2D6 (0.57) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL10768406 0.81 OPRM1 (0.63) CHRM2CYP2D6CHRM1OPRM1KCNH2
SCHEMBL1492481 0.81 OPRM1 (0.63) CHRM2CYP2D6CHRM1OPRM1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
US-20100112061-A1 Monophosphates as Mutual Prodrugs of Muscarinic Receptor Antagonists and Beta-Agonists for the Treatment of COPD And Chronic Bronchitis GILEAD SCIENCES, INC. 2010-05-06 US claimed
EP-2114972-A2 MONOPHOSPHATES AS MUTUAL PRODRUGS OF MUSCARINIC RECEPTOR ANTAGONISTS AND BETA-AGONISTS FOR THE TREATMENT OF COPD AND CHRONIC BRONCHITIS Gilead Sciences, Inc. (US) 2009-11-11 EP claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2008076269-A2 MONOPHOSPHATES AS MUTUAL PRODRUGS OF MUSCARINIC RECEPTOR ANTAGONISTS AND β-AGONISTS FOR THE TREATMENT OF COPD AND CHRONIC BRONCHITIS GILEAD SCIENCES, INC. (US) 2008-06-26 WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1273301-B1 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON SA (CH) 2006-09-06 EP claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-1273301-A2 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON S.A. (CH) 2003-01-08 EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
CN-122080069-A Phospholipid compounds and uses thereof 2026-05-26 CN disclosed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors REGENERON PHARMA (US) 2026-04-09 US disclosed
US-4764604-A Derivatives of gamma-cyclodextrin JANSSEN PHARMACEUTICA N.V. (BE) 1988-08-16 US disclosed
EP-0227173-A2 New method for the detection of specific binding agents and their corresponding bindable substances JANSSEN PHARMACEUTICA N.V. (BE) 1987-07-01 EP disclosed
EP-0197571-A2 Novel derivatives of gamma-cyclodextrin JANSSEN PHARMACEUTICA N.V. (BE) 1986-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 CHRM2 1957/4885CYP2D6 160/4885CHRM1 887/4885
US-20260097102-A1 Treatment Of Respiratory Disorders With Arachidonate 15-Lipoxygenase (ALOX15) Inhibitors ALOX15, ALOX15B, ALOX5 CHRM2 4475/4885CYP2D6 217/4885CHRM1 4534/4885
US-20100112061-A1 Monophosphates as Mutual Prodrugs of Muscarinic Receptor Antagonists and Beta-Agonists for the Treatment of COPD And Chronic Bronchitis ADRB1, ADRB2, CHRM3 CHRM2 5/4885CYP2D6 883/4885CHRM1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.