Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313657 | 0.84 | OPRM1 (0.41) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL27866775 | 0.81 | DRD2 (0.33) | SLC6A2SLC6A4SLC6A3DRD2 | |
| Tert-Butyl Formate SCHEMBL27935398 | 0.76 | GAA (0.40) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL28023819 | 0.75 | CYP1A2 (0.40) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL28023815 | 0.73 | CYP17A1 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL28086959 | 0.72 | FPR2 (0.41) | SLC6A2SLC6A4DRD2MEN1ALDH1A1 | |
| SCHEMBL28818066 | 0.72 | DRD2 (0.41) | DRD2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28821594 | 0.71 | ELANE (0.38) | SLC6A2SLC6A4SLC6A3MAPTPRKCA | |
| SCHEMBL24944595 | 0.69 | OPRM1 (0.47) | — | |
| SCHEMBL28818063 | 0.69 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282025-A | Melt-extruded solid dispersions containing apoptosis-inducing agents | ABBVIE INC | 2013-09-04 | — | — | CN | disclosed |