Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 11/20 | 0.62 |
| ▸ | YAP1 | P46937 | 1/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918011 | 0.92 | ACHE (0.56) | CACNA1HACHETERT | |
| SCHEMBL27918014 | 0.90 | CACNA1H (0.51) | CACNA1HYAP1TEAD4CACNA1CACHE | |
| SCHEMBL27936512 | 0.88 | NPSR1 (0.59) | CACNA1HACHEKDM4EALDH1A1TERT | |
| SCHEMBL27936536 | 0.87 | MEN1 (0.49) | CACNA1HACHEKDM4EALDH1A1TERT | |
| SCHEMBL27936466 | 0.74 | CACNA1H (0.68) | CACNA1HYAP1TEAD4CACNA1CTERT | |
| SCHEMBL27918010 | 0.71 | CACNA1H (0.73) | CACNA1HCACNA1CNT5EKDM4EALDH1A1 | |
| SCHEMBL28016088 | 0.68 | CACNA1H (0.84) | CACNA1HCACNA1CNT5EKDM4EALDH1A1 | |
| SCHEMBL27936621 | 0.68 | TERT (0.66) | CACNA1HTERT | |
| SCHEMBL27936553 | 0.68 | CACNA1H (0.64) | CACNA1HYAP1TEAD4CACNA1CACHE | |
| SCHEMBL30688878 | 0.67 | RNF114 (0.88) | CACNA1HYAP1TEAD4CACNA1CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304546-A | Pyrazoline derivatives comprising 1,4-benzodioxan structure, and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2013-09-18 | — | — | CN | disclosed |