Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 5/20 | 0.68 |
| ▸ | TERT | O14746 | 6/20 | 0.66 |
| ▸ | YAP1 | P46937 | 1/20 | 0.58 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936621 | 0.90 | TERT (0.66) | CACNA1HTERT | |
| SCHEMBL27936508 | 0.88 | TERT (0.69) | TERTCA1CA2CA9 | |
| SCHEMBL27918217 | 0.85 | TERT (0.56) | CACNA1HTERT | |
| SCHEMBL27936477 | 0.74 | CACNA1H (0.62) | CACNA1HTERTYAP1TEAD4CACNA1C | |
| SCHEMBL28016088 | 0.73 | CACNA1H (0.84) | CACNA1HCA12CA1CA2CA9 | |
| SCHEMBL14541217 | 0.71 | CA1 (0.74) | CACNA1HCA1CA2CA9 | |
| SCHEMBL14058372 | 0.71 | TERT (0.79) | TERT | |
| SCHEMBL10632933 | 0.71 | TERT (0.68) | CACNA1HTERTCACNA1C | |
| SCHEMBL29808004 | 0.70 | BRAF (1.00) | CACNA1HTERT | |
| SCHEMBL29807850 | 0.70 | BRAF (1.00) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304546-A | Pyrazoline derivatives comprising 1,4-benzodioxan structure, and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2013-09-18 | — | — | CN | disclosed |