Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.66 |
| ▸ | BCL2 | P10415 | 13/20 | 0.65 |
| ▸ | BECN1 | Q14457 | 8/20 | 0.65 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.62 |
| ▸ | RAF1 | P04049 | 1/20 | 0.61 |
| ▸ | BRAF | P15056 | 1/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936466 | 0.90 | CACNA1H (0.68) | TERTCACNA1H | |
| SCHEMBL27936508 | 0.88 | TERT (0.69) | TERT | |
| SCHEMBL27918217 | 0.87 | TERT (0.56) | TERTBCL2BECN1CACNA1HRAF1 | |
| SCHEMBL23269397 | 0.79 | BCL2 (1.00) | BCL2BECN1CACNA1H | |
| SCHEMBL14541165 | 0.78 | CACNA1H (0.78) | BCL2BECN1CACNA1H | |
| SCHEMBL23268979 | 0.77 | BCL2 (0.68) | BCL2BECN1CACNA1H | |
| SCHEMBL14541217 | 0.77 | CA1 (0.74) | BCL2BECN1CACNA1H | |
| SCHEMBL23269007 | 0.77 | BCL2 (1.00) | BCL2BECN1 | |
| SCHEMBL29808004 | 0.76 | BRAF (1.00) | TERTCACNA1HRAF1BRAFMAPK8 | |
| SCHEMBL23268937 | 0.75 | BCL2 (1.00) | BCL2BECN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304546-A | Pyrazoline derivatives comprising 1,4-benzodioxan structure, and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2013-09-18 | — | — | CN | disclosed |