Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936466 | 0.88 | CACNA1H (0.68) | TERTCA1CA2CA9 | |
| SCHEMBL27936621 | 0.88 | TERT (0.66) | TERT | |
| SCHEMBL14541214 | 0.83 | MEN1 (0.76) | NPSR1CA1CA2CA9MEN1 | |
| SCHEMBL27918217 | 0.79 | TERT (0.56) | TERTNPSR1MEN1KMT2A | |
| SCHEMBL14540886 | 0.77 | MEN1 (0.83) | NPSR1CA1CA2CA9MEN1 | |
| SCHEMBL27936512 | 0.76 | NPSR1 (0.59) | TERTNPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL25122626 | 0.76 | RNF114 (0.83) | L3MBTL1 | |
| SCHEMBL14540884 | 0.75 | KMT2A (0.87) | NPSR1CA1CA2CA9MEN1 | |
| SCHEMBL14058387 | 0.75 | TERT (0.74) | TERTCA1CA2CA9MEN1 | |
| SCHEMBL14058077 | 0.73 | TERT (0.71) | TERTCA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103304546-A | Pyrazoline derivatives comprising 1,4-benzodioxan structure, and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2013-09-18 | — | — | CN | disclosed |