Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918183 | 0.87 | XDH (0.44) | GPBAR1GRM5POLQKCNK3S1PR1 | |
| SCHEMBL28805571 | 0.85 | GPBAR1 (0.46) | GPBAR1PTGS2POLBNTRK1 | |
| SCHEMBL27936779 | 0.83 | GPBAR1 (0.55) | GPBAR1POLB | |
| SCHEMBL27918191 | 0.82 | GPBAR1 (0.53) | GPBAR1 | |
| SCHEMBL13732600 | 0.81 | GPBAR1 (0.51) | GPBAR1PTGS2POLBCSNK2A2CSNK2B | |
| SCHEMBL13735662 | 0.80 | GPBAR1 (0.52) | GPBAR1PTGS2POLB | |
| SCHEMBL27495331 | 0.78 | KMT2A (0.55) | GPBAR1PTGS2POLB | |
| SCHEMBL27936773 | 0.78 | GABRA5 (0.45) | GPBAR1PTGS2NTRK1 | |
| SCHEMBL2777083 | 0.78 | TDP1 (0.53) | GPBAR1PTGS2POLB | |
| SCHEMBL28805573 | 0.76 | ALDH1A1 (0.46) | GPBAR1S1PR1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313982-B | Phenyl-isoxazole derivatives and process for the preparation thereof | IL-YANG PHARM. CO.,LTD. (KR) | 2016-02-03 | — | — | CN | disclosed |
| CN-103313982-A | Phenyl-isoxazole derivatives and process for the preparation thereof | IL YANG PHARM CO LTD | 2013-09-18 | — | — | CN | disclosed |