Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810547 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNACYP2B6KCNN4HPGD | |
| SCHEMBL27951857 | 0.79 | KCNN4 (0.35) | ALDH1A1LMNACYP2B6KCNN4HPGD | |
| SCHEMBL27323649 | 0.72 | CYP2B6 (0.55) | LMNACYP2B6MEN1KMT2AMAPT | |
| SCHEMBL5569888 | 0.70 | KCNN4 (0.41) | ALDH1A1LMNACYP2B6KCNN4HPGD | |
| SCHEMBL6489440 | 0.68 | KCNN4 (0.42) | ALDH1A1KCNN4CCR6 | |
| SCHEMBL7777113 | 0.65 | KCNN4 (0.44) | ALDH1A1KCNN4CCR6 | |
| SCHEMBL9281500 | 0.65 | KCNN4 (0.39) | ALDH1A1KCNN4POLB | |
| SCHEMBL14354526 | 0.64 | CYP2B6 (0.46) | ALDH1A1CYP2B6MEN1KMT2APOLB | |
| SCHEMBL24826099 | 0.63 | KCNN4 (0.42) | ALDH1A1KCNN4CCR6GAA | |
| SCHEMBL17267041 | 0.63 | KCNN4 (0.42) | ALDH1A1KCNN4CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056919-B | Substituted sulfonamide derivatives | GRUENENTHAL GMBH | 2014-03-12 | — | — | CN | disclosed |