Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810568 | 0.85 | ADRB1 (0.46) | CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL27831055 | 0.85 | KMT2A (0.39) | KMT2AHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL28810547 | 0.79 | ALDH1A1 (0.36) | KCNN4HPGDNPC1LMNACYP2B6 | |
| SCHEMBL27939611 | 0.79 | ALDH1A1 (0.36) | KCNN4HPGDNPC1LMNACYP2B6 | |
| SCHEMBL27512467 | 0.73 | CYP2B6 (0.52) | LMNACYP2B6MEN1KMT2AHTR2A | |
| SCHEMBL27546772 | 0.72 | KCNN4 (0.45) | KCNN4GLALMNAALDH1A1MAPT | |
| SCHEMBL27323649 | 0.72 | CYP2B6 (0.55) | LMNACYP2B6MAPTMEN1KMT2A | |
| SCHEMBL4592612 | 0.65 | KCNN4 (0.46) | KCNN4GLALMNAALDH1A1MAPT | |
| SCHEMBL14354526 | 0.64 | CYP2B6 (0.46) | CYP2B6ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11498640 | 0.63 | KCNN4 (0.45) | KCNN4GLALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056919-B | Substituted sulfonamide derivatives | GRUENENTHAL GMBH | 2014-03-12 | — | — | CN | disclosed |