Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404286 | 0.79 | KDM4E (0.45) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL8687840 | 0.75 | KDM4E (0.45) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL1010304 | 0.74 | KDM4E (0.50) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL8388931 | 0.73 | KDM4E (0.50) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL77823 | 0.73 | KDM4E (0.67) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL29377777 | 0.73 | KDM4E (0.67) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL2438047 | 0.73 | KDM4E (0.67) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL4323659 | 0.73 | KDM4E (0.49) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL18727243 | 0.72 | KDM4E (0.57) | GAAKDM4EMAPTHTTTSHR | |
| SCHEMBL7502802 | 0.72 | ALDH1A1 (0.57) | GAAKDM4EMAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626761-B | Benazepine compound and the application as antitumor drug thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-103626761-A | Benazepine compound and application thereof as antitumor drug | CISEN PHARMACEUTICAL CO LTD | 2014-03-12 | — | — | CN | disclosed |