Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804060 | 0.90 | L3MBTL1 (0.39) | MEN1KMT2ALMNAPOLBTDP1 | |
| SCHEMBL1131379 | 0.88 | MEN1 (0.44) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL3487980 | 0.86 | RAB9A (0.41) | MEN1KMT2ARAB9APOLBTDP1 | |
| SCHEMBL6543570 | 0.86 | MERTK (0.40) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL27921215 | 0.85 | MEN1 (0.36) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL27782510 | 0.85 | RAB9A (0.33) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL27804048 | 0.84 | HSPB1 (0.37) | MEN1KMT2ALMNAPOLBTDP1 | |
| SCHEMBL27921211 | 0.83 | ALDH1A1 (0.36) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL27804034 | 0.83 | HSPB1 (0.40) | MEN1KMT2ALMNAPOLBTDP1 | |
| SCHEMBL27782480 | 0.82 | ABL1 (0.34) | MEN1KMT2ARAB9ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679298-B | Fused bicyclic heteroaryl derivatives | DAIICHI SANKYO CO LTD | 2013-10-23 | — | — | CN | disclosed |