SCHEMBL27943045

SCHEMBL27943045

Cc1nc(NC(=O)C(N)C(C)O)c2ncn([C@]3(C(N)=O)O[C@H](CO)[C@@H](O)[C@]3(O)S(=O)(=O)O)c2n1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27918607 0.88 ADORA3 (0.31) TARS1
SCHEMBL31406475 0.80 ADORA2A (0.36) TARS1
SCHEMBL31326251 0.79 TARS1 (0.36) TARS1
SCHEMBL28494144 0.79 TARS1 (0.36) TARS1
SCHEMBL27196595 0.77 TARS1 (0.33) TARS1
SCHEMBL28304158 0.76 TARS1 (0.34) TARS1
SCHEMBL28119453 0.75 ADORA3 (0.34) —
SCHEMBL28120771 0.74 TARS1 (0.35) TARS1
SCHEMBL31192374 0.74 ADORA2A (0.35) —
SCHEMBL28857389 0.72 ADORA3 (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103687957-A Engineered nucleic acids and methods for their use in non-human vertebrates modeRNA Therapeutics 2014-03-26 — — CN claimed
CN-104114572-A Modified nucleosides, nucleotides and nucleic acid compositions MODERNA THERAPEUTICS INC 2014-10-22 — — CN disclosed
CN-103974724-A Modified nucleosides, nucleotides and nucleic acids and uses thereof modeRNA Therapeutics 2014-08-06 — — CN disclosed
CN-103687957-A Engineered nucleic acids and methods for their use in non-human vertebrates modeRNA Therapeutics 2014-03-26 — — CN disclosed
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