SCHEMBL809254

SCHEMBL809254

N#Cc1c(F)c(F)c(F)c(C#N)c1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.38
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4094768 1.00 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL22322143 1.00 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL250738 0.96 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL57543 0.93 TRPV4 (0.41) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL9625848 0.93 TRPV4 (0.41) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL31612588 0.89 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL30542039 0.89 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
Ammonia Solution, Strong SCHEMBL27947136 0.89 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL809214 0.89 TRPV4 (0.39) TRPV4MEN1ALDH1A1TP53CYP3A4
SCHEMBL16581505 0.86 TRPV4 (0.38) TRPV4MEN1ALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3371268-B1 CYANOACRYLATE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2025-04-02 EP claimed
CN-119330857-A Crystalline material with photochromic response and preparation method thereof 河南工业大学 2025-01-21 CN claimed
CN-114512719-B Eutectic solvent-based electrolyte and application thereof 中国科学院青岛生物能源与过程研究所 2024-12-03 CN claimed
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US claimed
CN-118598860-A Thermal activation delayed fluorescent material capable of being processed by solution method and preparation method and application thereof 东南大学 2024-09-06 CN claimed
CN-118531524-A Organic micro-nano crystal-based large-area multicolor fluorescence emitting fiber and preparation method and application thereof 苏州大学 2024-08-23 CN claimed
CN-118444360-A Charge transfer type organic eutectic material, scintillator eutectic film, and preparation methods and applications thereof 西北工业大学 2024-08-06 CN claimed
CN-117855377-A Composite pole piece, preparation method and application thereof, and low-temperature lithium ion battery 中科超能(深圳)新能源科技有限公司 2024-04-09 CN claimed
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 CN claimed
WO-2002002504-A1 PRODUCTION METHOD FOR BENZENEDIMETHANOL COMPOUND SHOWA DENKO K.K. (JP) 2002-01-10 WO claimed
US-5583091-A COMPRISES A HALOGENATED AROMATIC 1,2- OR 1,3-DINITRILE, A SUBSTITUTED UREA AND A HALOGEN-CONTAINING AROMATIC ALKYL SULFOXIDE OR SULFONE ZENECA LIMITED (GB) 1996-12-10 US claimed
US-5401757-A Dinitriles, urea and sulfur oxygen pyridine compounds ZENECA LIMITED (GB) 1995-03-28 US claimed
EP-0390394-B1 Composition and use ZENECA LTD (GB) 1994-06-15 EP claimed
EP-0307897-B1 TRIFLUOROBENZENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME SDS Biotech K.K. (JP) 1993-03-17 EP claimed
US-5125967-A For water supply systems, paints, coatings IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US claimed
EP-0390394-A2 Composition and use ZENECA LIMITED (GB) 1990-10-03 EP claimed
US-4925966-A DEFLUORINATION OF TETRAFLUOROISOPHTHALONITRILE WITH METAL HYDRIDE TO MAKE 2,4,5-TRIFLURORISOPHTHALONITRILE SDS BIOTECH K.K. (JP) 1990-05-15 US claimed
EP-0307897-A1 Trifluorobenzene compounds and process for producing the same SDS Biotech K.K. (JP) 1989-03-22 EP claimed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US claimed