Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22322143 | 1.00 | TRPV4 (0.38) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL809254 | 1.00 | TRPV4 (0.38) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL250738 | 0.96 | TRPV4 (0.39) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL57543 | 0.93 | TRPV4 (0.41) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL9625848 | 0.93 | TRPV4 (0.41) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL31612588 | 0.89 | TRPV4 (0.39) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL30542039 | 0.89 | TRPV4 (0.39) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL27947136 | 0.89 | TRPV4 (0.39) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL809214 | 0.89 | TRPV4 (0.39) | TRPV4MEN1ALDH1A1TP53CYP3A4 | |
| SCHEMBL16581505 | 0.86 | TRPV4 (0.38) | TRPV4MEN1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401799-B1 | PRODUCTION PROCESS FOR HALOGENATED AROMATIC METHYLAMINE | SHOWA DENKO KK (JP) | 2009-05-13 | — | — | EP | disclosed |