SCHEMBL27949017

SCHEMBL27949017

CCC1=C(C)CC(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.38
PTGS1 P23219 5/20 0.38
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
KMT2A Q03164 1/20 0.36
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PTPN1 P18031 1/20 0.33
TP53 P04637 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
ABCB11 O95342 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MT-CO2 P00403 1/20 0.31
HTR1A P08908 1/20 0.31
ADORA3 P0DMS8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27933609 0.85 CFTR (0.36) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27948982 0.82 ESR1 (0.39) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27933440 0.78 PTGS2 (0.43) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27949026 0.76 PTGS2 (0.42) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27933549 0.75 NOS1 (0.36) ALDH1A1
SCHEMBL27933471 0.73 PTGS1 (0.37) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL20722299 0.73 ALDH1A1 (0.42) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27933484 0.72 CFTR (0.41) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL27933487 0.71 ESR1 (0.42) PTGS2PTGS1CFTRGOPCKMT2A
SCHEMBL8197843 0.70 CFTR (0.52) PTGS2PTGS1CFTRGOPCKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103476735-A Method for producing 1-hexene SUMITOMO CHEMICAL CO 2013-12-25 CN disclosed