SCHEMBL27952004

SCHEMBL27952004

CCC(=O)Oc1cccc(Cl)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.47
ALDH1A1 P00352 2/20 0.46
LMNA P02545 3/20 0.43
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 2/20 0.43
GLA P06280 2/20 0.43
GAA P10253 2/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HTT P42858 1/20 0.43
ACHE P22303 3/20 0.43
POLB P06746 2/20 0.41
NLRP3 Q96P20 1/20 0.41
ALOX15 P16050 1/20 0.41
ESR1 P03372 2/20 0.40
HIF1A Q16665 2/20 0.40
MAPT P10636 2/20 0.39
ELANE P08246 1/20 0.39
USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11285158 0.87 MRGPRX4 (0.45) MRGPRX4ALDH1A1LMNAKMT2AKDM4E
SCHEMBL1261928 0.84 HTR1D (0.46) MRGPRX4ALDH1A1KMT2AKDM4EGAA
SCHEMBL578720 0.84 ELANE (0.46) ALDH1A1KMT2AKDM4EHPGDHTT
SCHEMBL9799609 0.84 ELANE (0.46) ALDH1A1KMT2AKDM4EHPGDHTT
SCHEMBL27964082 0.83 ACHE (0.41) ALDH1A1KMT2AKDM4EMAPK1ACHE
SCHEMBL15547750 0.83 KMT2A (0.43) ALDH1A1KMT2AKDM4EMAPK1ACHE
SCHEMBL1750794 0.82 POLB (0.53) ALDH1A1LMNAKMT2AKDM4EGLA
Hydrochloric Acid SCHEMBL27455927 0.82 ELANE (0.45) ALDH1A1KMT2AKDM4EHPGDHTT
SCHEMBL27714284 0.81 MRGPRX4 (0.46) MRGPRX4ALDH1A1KMT2AHPGDACHE
SCHEMBL24309423 0.81 HPGD (0.50) MRGPRX4ALDH1A1LMNAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103626691-B The preparation method of ZEN 90160 Shanghai Heben-Eastsun Medicaments Co., Ltd. (CN) 2015-10-21 CN disclosed
CN-103626691-A Picoxystrobin preparation method SHANGHAI HEBEN EASTSUN MEDICAMENTS CO LTD 2014-03-12 CN disclosed