SCHEMBL9799609

SCHEMBL9799609

CCC(=O)Oc1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.45
PTK2B Q14289 1/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
PKM P14618 1/20 0.45
CXCL8 P10145 1/20 0.45
POLB P06746 1/20 0.44
BCHE P06276 1/20 0.44
ALOX15 P16050 1/20 0.44
HPGD P15428 3/20 0.43
ESR1 P03372 1/20 0.43
HIF1A Q16665 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
ACHE P22303 1/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL578720 1.00 ELANE (0.46) ELANEALDH1A1MAPTPTK2BMEN1
Hydrochloric Acid SCHEMBL27455927 0.98 ELANE (0.45) ELANEALDH1A1MAPTPTK2BMEN1
SCHEMBL8435546 0.86 ALOX15 (0.55) ELANEALDH1A1MAPTMEN1KMT2A
SCHEMBL1261928 0.85 HTR1D (0.46) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL6917578 0.85 ALDH1A1 (0.54) ALDH1A1MAPTPTK2BMEN1KMT2A
SCHEMBL8496813 0.84 PTK2B (0.47) ALDH1A1MAPTPTK2BMEN1KMT2A
SCHEMBL15547750 0.84 KMT2A (0.43) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL27952004 0.84 MRGPRX4 (0.47) ELANEALDH1A1MAPTKMT2APOLB
SCHEMBL27964082 0.84 ACHE (0.41) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL28189795 0.82 MEN1 (0.50) MAPTPTK2BMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041663-A Plant safening agents CIBA-GEIGY CORPORATION (US) 1991-08-20 US disclosed
US-5032169-A Antidotes for herbicides CIBA-GEIGY CORPORATION (US) 1991-07-16 US disclosed
US-4759789-A Treating locus of plant before or during application of herbicide with oxime ether compound CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
US-4566901-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-01-28 US disclosed
EP-0094348-A1 Oxime ethers, process for their preparation, agents containing the oxime ethers and their use CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed