Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27952004 | 0.87 | MRGPRX4 (0.47) | MRGPRX4HTTALDH1A1KMT2AKDM4E | |
| SCHEMBL4573844 | 0.85 | KMT2A (0.45) | MRGPRX4HTTALDH1A1MEN1KMT2A | |
| SCHEMBL6917578 | 0.85 | ALDH1A1 (0.54) | HTTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28423131 | 0.84 | KDM4E (0.44) | HTTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27942332 | 0.83 | MEN1 (0.50) | ALDH1A1MEN1KMT2AKDM4ERECQL | |
| SCHEMBL22230490 | 0.83 | MRGPRX4 (0.44) | MRGPRX4HTTALDH1A1MEN1KMT2A | |
| SCHEMBL11277533 | 0.80 | KMT2A (0.46) | HTTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9312497 | 0.79 | KMT2A (0.59) | ALDH1A1MEN1KMT2AKDM4ERECQL | |
| SCHEMBL24309423 | 0.78 | HPGD (0.50) | MRGPRX4HTTALDH1A1MEN1KMT2A | |
| SCHEMBL21728175 | 0.78 | ACHE (0.59) | MRGPRX4HTTALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045088-A1 | Process for preparing substituted p-chlorophenyl aliphatic nitriles | STAUFFER CHEMICAL COMPANY (US) | 1982-02-03 | — | — | EP | disclosed |