SCHEMBL578720

SCHEMBL578720

CCC(=O)Oc1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.45
PTK2B Q14289 1/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
PKM P14618 1/20 0.45
CXCL8 P10145 1/20 0.45
POLB P06746 1/20 0.44
BCHE P06276 1/20 0.44
ALOX15 P16050 1/20 0.44
HPGD P15428 3/20 0.43
ESR1 P03372 1/20 0.43
HIF1A Q16665 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
ACHE P22303 1/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9799609 1.00 ELANE (0.46) ELANEALDH1A1MAPTPTK2BMEN1
Hydrochloric Acid SCHEMBL27455927 0.98 ELANE (0.45) ELANEALDH1A1MAPTPTK2BMEN1
SCHEMBL8435546 0.86 ALOX15 (0.55) ELANEALDH1A1MAPTMEN1KMT2A
SCHEMBL1261928 0.85 HTR1D (0.46) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL6917578 0.85 ALDH1A1 (0.54) ALDH1A1MAPTPTK2BMEN1KMT2A
SCHEMBL8496813 0.84 PTK2B (0.47) ALDH1A1MAPTPTK2BMEN1KMT2A
SCHEMBL15547750 0.84 KMT2A (0.43) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL27952004 0.84 MRGPRX4 (0.47) ELANEALDH1A1MAPTKMT2APOLB
SCHEMBL27964082 0.84 ACHE (0.41) ELANEALDH1A1MEN1KMT2AALOX15
SCHEMBL28189795 0.82 MEN1 (0.50) MAPTPTK2BMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN claimed
CN-102250114-B Preparation method of clopidogel and sulfate thereof QINGDAO HUANGHAI PHARMACEUTICAL CO LTD 2014-02-26 CN claimed
CN-101519401-B Intermediate (S)-2-(2-thiophene ethylamine)(2-chlorphenyl)methyl acetate of clopidogrel and method for preparing salts thereof SHANGHAI ECUST BIOMEDICINE CO LTD 2012-12-05 CN claimed
CN-102438450-A fruit thinning agent TAMINCO NV 2012-05-02 CN claimed
CN-102250114-A Preparation method of clopidogel and sulfate thereof QINGDAO HUANGHAI PHARMACEUTICAL CO LTD 2011-11-23 CN claimed
CN-101909451-A Fungicidal mixtures II BASF SE 2010-12-08 CN claimed
CN-101519401-A Intermediate (S)-2-(2-thiophene ethylamine)(2-chlorphenyl)methyl acetate of clopidogrel and method for preparing salts thereof SHANGHAI ECUST BIOMEDICINE CO 2009-09-02 CN claimed
CN-110300744-B Compounds for optically active devices 爱尔兰眼力健公司 2023-09-15 CN disclosed
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN disclosed
CN-116655652-A New synthesis method of clopidogrel 宿迁盛基医药科技有限公司 2023-08-29 CN disclosed
CN-106061267-B Application of chemical agent in stone fruit flower thinning 精细农用化学品有限公司 2022-02-01 CN disclosed
US-20210387996-A1 TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE HOFFMANN-LA ROCHE INC. (US) 2021-12-16 US disclosed
CN-111606923-B Synthesis method of racemic clopidogrel 武汉理工大学 2021-08-24 CN disclosed
US-4347177-A Compounds and methods of making them BURROUGHS WELLCOME CO. (US) 1982-08-31 US disclosed
US-4347382-A 3H Labeled compounds BURROUGHS WELLCOME CO. (US) 1982-08-31 US disclosed
US-4347176-A Compounds and methods of making same BURROUGHS WELLCOME CO. (US) 1982-08-31 US disclosed
US-4347178-A Compounds and methods of making BURROUGHS WELLCOME CO. (US) 1982-08-31 US disclosed
EP-0038071-A2 New unlabelled and radioactive labelled derivatives of butylamino propiophenone, their preparation, immunogens obtained from the unlabelled derivatives and a process for immunogen preparation, antisera raised using the immunogens and a method for raising antisera, a radioimmunoassay method and a test kit for use in the assay method THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-21 EP disclosed
US-4153707-A Fungicidal isoxazolyl phenols and method of use THE UPJOHN COMPANY (US) 1979-05-08 US disclosed
US-4065574-A New method for controlling fungi using 4-chromone, 4-chromanone, 4-chromone oxime and 4-chromanone oxime compounds THE UPJOHN COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210387996-A1 TRICYCLIC COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS DISEASE TOP2B, HAVCR2, SLC10A1 ELANE 2526/4885ALDH1A1 1239/4885MAPT 3771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.