Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RGS4 | P49798 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383844 | 0.83 | SLC6A3 (0.41) | SIGMAR1ACHEGAANPSR1 | |
| SCHEMBL21201399 | 0.74 | ALDH1A1 (0.33) | LMNAPOLBALDH1A1GAATHRB | |
| SCHEMBL21516061 | 0.71 | LMNA (0.41) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL17126135 | 0.71 | LMNA (0.41) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL9162755 | 0.69 | — | — | |
| SCHEMBL28401940 | 0.67 | MC4R (0.44) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL13433740 | 0.67 | GAA (0.47) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL28946773 | 0.66 | POLB (0.50) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL6772339 | 0.66 | SIGMAR1 (0.37) | LMNAPOLBSIGMAR1MC4RTSHR | |
| SCHEMBL13801222 | 0.65 | SIGMAR1 (0.60) | LMNAPOLBSIGMAR1MC4RACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987077-A | Synthetic method of 2, 3-dihydro indolizine compound | 中国科学院兰州化学物理研究所 | 2023-11-03 | — | — | CN | disclosed |
| CN-102056878-B | Polyfluoro-1-alkane and method of manufacture therefor | UNIMATEC CO LTD | 2014-02-12 | — | — | CN | disclosed |