SCHEMBL868520

SCHEMBL868520

O=C1COc2ccccc2OC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.52
ITGB2 P05107 1/20 0.52
ICAM1 P05362 1/20 0.52
ITGAL P20701 1/20 0.52
MAOB P27338 3/20 0.46
MAOA P21397 2/20 0.46
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
HTT P42858 1/20 0.46
TSHR P16473 2/20 0.44
PKM P14618 1/20 0.44
CYP1A2 P05177 1/20 0.43
DAPK3 O43293 1/20 0.41
RET P07949 1/20 0.41
PRKACA P17612 1/20 0.41
GRK5 P34947 1/20 0.41
CDK8 P49336 1/20 0.41
GSK3A P49840 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30450885 0.80 CYP1A2 (0.54) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL3962887 0.80 CYP1A2 (0.54) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL6108899 0.79 CYP2A6 (0.50) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL279547 0.77 ABCG2 (0.46) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL29966720 0.77 ABCG2 (0.46) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL10460744 0.75 PKM (0.48) MAOBMAOASMN1; SMN2TSHRPKM
SCHEMBL6068686 0.74 OXTR (0.37) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL15569568 0.74 GAA (0.52) MAOBMAOATSHRPKMALOX5
SCHEMBL1593497 0.74 MAOB (0.39) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL6569085 0.74 MAP3K14 (0.36) SMN1; SMN2TSHRNPC1RAB9AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109640937-B Antiperspirant or deodorant compositions 弗门尼舍有限公司 2022-06-14 CN claimed
CN-114096235-A Antimicrobial compositions 弗门尼舍有限公司 2022-02-25 CN claimed
CN-110099993-B High impact perfume microcapsules of balanced density 弗门尼舍有限公司 2021-08-24 CN claimed
US-10336966-B2 Fragrance compositions and uses thereof THE PROCTER & GAMBLE COMPANY (US) 2019-07-02 US claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-9814661-B2 Fragrance compositions THE PROCTER & GAMBLE COMPANY (US) 2017-11-14 US claimed
EP-3197424-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP claimed
EP-2961374-B1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-01-25 EP claimed
WO-2016049398-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO claimed
EP-2961374-A1 FRAGRANCE COMPOSITIONS The Procter & Gamble Company (US) 2016-01-06 EP claimed
US-8754028-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2014-06-17 US claimed
WO-2013053102-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2013-04-18 WO claimed
US-20100152083-A1 Perfume Systems PROCTER & GAMBLE COMPANY, THE 2010-06-17 US claimed
EP-2162525-A1 PERFUMED HOUSEHOLD PRODUCTS AND METHODS FOR PRESERVING PERFUME INTEGRITY AND EXTENDING FRAGRANCE LIFE The Procter & Gamble Company (US) 2010-03-17 EP claimed
US-20090218251-A1 PERFUMED HOUSEHOLD PRODUCTS AND METHODS FOR PRESERVING PERFUME INTEGRITY AND EXTENDING FRAGRANCE LIFE WOO RICKY AH-MAN 2009-09-03 US claimed
US-7550416-B2 Perfumed household products and methods for preserving perfume integrity and extending fragrance life THE PROCTER & GAMBLE COMPANY (US) 2009-06-23 US claimed
US-20090000979-A1 Perfumed household products and methods for preserving perfume integrity and extending fragrance life PROCTER & GAMBLE COMPANY, THE 2009-01-01 US claimed
US-20090005280-A1 PERFUMED HOUSEHOLD PRODUCTS AND METHODS FOR PRESERVING PERFUME INTEGRITY AND EXTENDING FRAGRANCE LIFE PROCTER & GAMBLE COMPANY, THE 2009-01-01 US claimed
WO-2009001320-A1 PERFUMED HOUSEHOLD PRODUCTS AND METHODS FOR PRESERVING PERFUME INTEGRITY AND EXTENDING FRAGRANCE LIFE THE PROCTER & GAMBLE COMPANY (US) 2008-12-31 WO claimed
EP-1405851-A1 Method for producing seven-membered diether compounds and intermediates thereof Takasago International Corporation (JP) 2004-04-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336966-B2 Fragrance compositions and uses thereof CUTA, DPM1, PLIN5 ABCG2 3483/4885ITGB2 3262/4885ICAM1 3331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.