Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792537 | 0.91 | KDM4E (0.42) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA | |
| SCHEMBL2796620 | 0.88 | ALDH1A1 (0.38) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA | |
| SCHEMBL4018674 | 0.86 | NPSR1 (0.37) | KDM4EALDH1A1L3MBTL1FTOCYP2C19 | |
| SCHEMBL3262058 | 0.84 | CYP2C19 (0.37) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA | |
| SCHEMBL2795766 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA | |
| SCHEMBL2796083 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1CYP2C19CYP1A2HSD17B10 | |
| SCHEMBL3531293 | 0.71 | DPP4 (0.42) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL3257816 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA | |
| SCHEMBL1422926 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1HSD17B10POLB | |
| SCHEMBL2796002 | 0.66 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | HPD, HAAO, HCAR2 | KDM4E 1581/4885ALDH1A1 475/4885L3MBTL1 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.