Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017611 | 0.83 | KDM4E (0.35) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL2795766 | 0.82 | KDM4E (0.46) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL13232457 | 0.81 | KDM4E (0.53) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL3258125 | 0.81 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL2792537 | 0.77 | KDM4E (0.42) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL4515102 | 0.71 | ALDH1A1 (0.49) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL9300611 | 0.70 | KDM4E (0.55) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL4509989 | 0.69 | KDM4E (0.44) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL13232454 | 0.69 | ALDH1A1 (0.44) | KDM4EMAPTALDH1A1HSD17B10HPGD | |
| SCHEMBL25117949 | 0.69 | KDM4E (0.54) | KDM4EMAPTALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008151735-A2 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYL CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | HPD, HAAO, HCAR2 | KDM4E 1581/4885MAPT 3950/4885ALDH1A1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.