Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258125 | 0.89 | ALDH1A1 (0.38) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL2796002 | 0.83 | KDM4E (0.47) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL3257816 | 0.82 | KDM4E (0.36) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL3262058 | 0.78 | CYP2C19 (0.37) | KDM4EMAPTALDH1A1HPGDL3MBTL1 | |
| SCHEMBL5774361 | 0.72 | CDK4 (0.32) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL5771022 | 0.70 | MEN1 (0.33) | MAPTALDH1A1LMNA | |
| SCHEMBL4018674 | 0.69 | NPSR1 (0.37) | KDM4EGAAMAPTALDH1A1HPGD | |
| SCHEMBL4017079 | 0.68 | CRHR1 (0.35) | KDM4EALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL5283300 | 0.68 | CRHR1 (0.37) | KDM4EGAAMAPTCYP3A4RAB9A | |
| SCHEMBL4229924 | 0.68 | KDM4E (0.42) | KDM4EMAPTALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |