Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2798096 | 0.86 | CHRNB2 (0.33) | TSHR | |
| SCHEMBL4902055 | 0.83 | CHRNB2 (0.34) | TSHR | |
| SCHEMBL4051767 | 0.80 | DNM1 (0.35) | CES2 | |
| Hydrochloric Acid SCHEMBL366719 | 0.77 | CHRM5 (0.45) | TSHR | |
| SCHEMBL294859 | 0.75 | — | — | |
| SCHEMBL1598351 | 0.75 | DNM1 (0.33) | — | |
| SCHEMBL8045306 | 0.75 | SLC22A1 (0.62) | SLC22A1TSHRHSD17B10 | |
| SCHEMBL22318912 | 0.74 | HTT (0.52) | CES2 | |
| SCHEMBL758122 | 0.74 | CHRM5 (0.43) | TSHR | |
| SCHEMBL1633705 | 0.74 | CES2 (0.59) | CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168282-A1 | DISPERSION COMPRISING INORGANIC PARTICLES, WATER, AND AT LEAST ONE POLYMERIC ADDITIVE | EVONIK ROEHM GMBH (DE) | 2010-07-01 | — | — | US | disclosed |