Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079390 | 0.82 | RAB9A (0.53) | CYP3A4CYP2C9ALOX12ALDH1A1KMT2A | |
| SCHEMBL29705179 | 0.82 | RAB9A (0.53) | CYP3A4CYP2C9ALOX12ALDH1A1KMT2A | |
| SCHEMBL6200210 | 0.78 | CHRNB2 (0.66) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL1017795 | 0.78 | CYP3A4 (0.89) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL27559308 | 0.77 | BCAT2 (0.53) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL30042190 | 0.77 | BCAT2 (0.53) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL8809646 | 0.77 | CHRNB2 (0.69) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL30041780 | 0.77 | SLC6A3 (0.54) | ALDH1A1HTTMEN1KMT2ALMNA | |
| SCHEMBL1017796 | 0.76 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA4CYP3A4 | |
| SCHEMBL2220494 | 0.76 | SMO (0.64) | ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833672-A | Preparation method of N-butyl-5-phenylthiazole-4-formamide derivative | UNIV CHINA PHARMA | 2014-06-04 | — | — | CN | claimed |