Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | MGAM | O43451 | 5/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | SI | P14410 | 5/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965687 | 0.80 | P2RX7 (0.62) | P2RX7ADRA1DHTR2AADRA1BSLC9A1 | |
| Hydrochloric Acid SCHEMBL27969523 | 0.79 | P2RX7 (0.61) | P2RX7ADRA1DHTR2AADRA1BSLC9A1 | |
| SCHEMBL15748342 | 0.78 | SIGMAR1 (0.55) | HTR2A | |
| SCHEMBL27965846 | 0.76 | HCAR3 (0.40) | P2RX7HCAR3 | |
| SCHEMBL17192209 | 0.75 | KCNH2 (0.63) | HTR2A | |
| SCHEMBL28650701 | 0.74 | SLC9A1 (0.60) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28675633 | 0.74 | SLC9A1 (0.60) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL17103124 | 0.74 | SLC9A1 (0.51) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28669951 | 0.74 | SLC9A1 (0.60) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL19911445 | 0.73 | SLC9A1 (0.58) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | claimed |
| CN-103833658-A | Benzotriazole-based piperazine compound as well as preparation method and pharmaceutical composition thereof | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |