Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411974 | 0.88 | HRH3 (0.45) | MAPTKMT2ACYP11B1CYP11B2TP53 | |
| SCHEMBL19415197 | 0.85 | KMT2A (0.52) | MAPTKMT2ACALM1TP53LTA4H | |
| SCHEMBL9430612 | 0.81 | CALM1 (0.46) | MAPTKMT2ACALM1CYP11B1CYP11B2 | |
| SCHEMBL5109315 | 0.81 | CALM1 (0.46) | CALM1CYP11B1CYP11B2LTA4HLMNA | |
| SCHEMBL18069635 | 0.80 | HRH3 (0.45) | MAPTKMT2ACYP11B1CYP11B2TP53 | |
| SCHEMBL18763010 | 0.80 | TP53 (0.46) | MAPTKMT2ACALM1TP53LTA4H | |
| SCHEMBL487617 | 0.79 | HRH3 (0.55) | MAPTKMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL30398570 | 0.79 | HRH3 (0.55) | MAPTKMT2ALMNACYP1A2CYP2D6 | |
| SCHEMBL22957984 | 0.78 | LTA4H (0.40) | MAPTKMT2ACALM1CYP11B1CYP11B2 | |
| SCHEMBL18924305 | 0.77 | LTA4H (0.43) | MAPTKMT2ACALM1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |
| CN-104109155-A | Novel compounds | TANABE SEIYAKU CO | 2014-10-22 | — | — | CN | disclosed |
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |