Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14895362 | 0.87 | NOTUM (0.60) | NOTUMALDH1A1NPC1CYP1A2CYP2C19 | |
| SCHEMBL18711265 | 0.81 | NOTUM (0.69) | NOTUMDRD2DRD4ALDH1A1NPC1 | |
| SCHEMBL4111447 | 0.75 | LMNA (0.62) | LMNATP53 | |
| SCHEMBL30040609 | 0.75 | LMNA (0.62) | LMNATP53 | |
| SCHEMBL9204053 | 0.75 | NOTUM (0.64) | NOTUMDRD2DRD4ALDH1A1NPC1 | |
| SCHEMBL23369283 | 0.74 | LMNA (0.48) | NOTUMLMNATP53DRD2DRD4 | |
| SCHEMBL14229140 | 0.73 | NOTUM (0.50) | NOTUMDRD2DRD4ALDH1A1NPC1 | |
| SCHEMBL22064485 | 0.72 | LMNA (0.46) | NOTUMLMNATP53DRD2DRD4 | |
| SCHEMBL7993369 | 0.72 | DRD2 (0.54) | NOTUMDRD2DRD4ALDH1A1NPC1 | |
| SCHEMBL7593171 | 0.70 | NOTUM (0.57) | NOTUMDRD2DRD4ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889969-A | Novel process | GIVAUDAN SA | 2014-06-25 | — | — | CN | disclosed |