SCHEMBL78141

SCHEMBL78141

c1ccc(Oc2cccnc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
CYP11B1 P15538 1/20 0.65
CYP11B2 P19099 1/20 0.65
CYP19A1 P11511 3/20 0.63
LTA4H P09960 4/20 0.57
TSHR P16473 1/20 0.57
HTT P42858 2/20 0.53
ALDH1A1 P00352 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
TP53 P04637 1/20 0.51
RECQL P46063 1/20 0.51
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
TRPV6 Q9H1D0 1/20 0.49
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29500180 1.00 LMNA (0.72) LMNATDP1CYP11B1CYP11B2CYP19A1
Hydrochloric Acid SCHEMBL9386460 0.98 LMNA (0.69) LMNATDP1CYP11B1CYP11B2CYP19A1
SCHEMBL27968872 0.98 LMNA (0.69) LMNATDP1CYP11B1CYP11B2CYP19A1
Bromide SCHEMBL9391382 0.98 LMNA (0.69) LMNATDP1CYP11B1CYP11B2CYP19A1
SCHEMBL16114401 0.93 LMNA (0.75) LMNATDP1CYP11B1CYP11B2CYP19A1
SCHEMBL30535283 0.93 LMNA (0.82) LMNATDP1CYP11B1CYP11B2CYP19A1
SCHEMBL676142 0.93 LMNA (0.82) LMNATDP1CYP11B1CYP11B2CYP19A1
Potassium SCHEMBL6776357 0.90 LMNA (0.78) LMNATDP1CYP11B1CYP11B2CYP19A1
SCHEMBL6510014 0.88 TDP1 (0.58) LMNATDP1CYP11B1CYP11B2CYP19A1
Sulfuric Acid SCHEMBL11641651 0.88 TDP1 (0.58) LMNATDP1CYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070231390-A1 Formulations including hygroscopic compounds ANDRX LABS, LLC (US) 2007-10-04 US claimed
WO-1994002143-A1 USE OF 3-PHENOXYPYRIDINE IN THE TREATMENT OF PSYCHOMOTOR STIMULANT ADDICTION WARNER-LAMBERT COMPANY (US) 1994-02-03 WO claimed
US-5232934-A Administering 3-phenoxypyridine(or its acid addition salts) as nontoxic substitute for addictive stimulants WARNER-LAMBERT CO. (US) 1993-08-03 US claimed
EP-0345787-B1 DRUG IN COMBINATION WITH FLAVOR MASKING AGENT AND METHOD FOR MAKING SAME WARNER-LAMBERT COMPANY (US) 1992-11-11 EP claimed
US-4910023-A Containing silica WARNER-LAMBERT COMPANY (US) 1990-03-20 US claimed
EP-0345787-A2 Drug in combination with flavor masking agent and method for making same WARNER-LAMBERT COMPANY (US) 1989-12-13 EP claimed
EP-0116781-B1 PHARMACEUTICAL COMPOSITIONS IN ORAL DOSAGE FORM WARNER-LAMBERT COMPANY (US) 1989-08-02 EP claimed
EP-0239527-A2 Composition adopted for use as a transdermal formulation WARNER-LAMBERT COMPANY (US) 1987-09-30 EP claimed
EP-0116781-A1 Pharmaceutical compositions in oral dosage form WARNER-LAMBERT COMPANY (US) 1984-08-29 EP claimed
US-4434169-A MEMORY LOSS, 3-PHENOXYPYRIDINE WARNER-LAMBERT COMPANY (US) 1984-02-28 US claimed
US-4128555-A 3-Phenoxypyridine monosulfate and a method for its production WARNER-LAMBERT COMPANY (US) 1978-12-05 US claimed
US-4067983-A PSYCHOSTIMULATION USING 3-PHENOXYPYRIDINE PARKE, DAVIS & COMPANY (US) 1978-01-10 US claimed
US-4061756-A Methods for treating cardiovascular disorders PARKE, DAVIS & COMPANY (US) 1977-12-06 US claimed
JP-2036130-A None JP disclosed
JP-2028155-A None JP disclosed
US-20260007660-A1 TREATMENT AND PREVENTION OF SLEEP DISORDERS PURDUE PHARMA L.P. (US) 2026-01-08 US disclosed
US-4067983-A PSYCHOSTIMULATION USING 3-PHENOXYPYRIDINE PARKE, DAVIS & COMPANY (US) 1978-01-10 US disclosed
US-4067983-A PSYCHOSTIMULATION USING 3-PHENOXYPYRIDINE PARKE, DAVIS & COMPANY (US) 1978-01-10 US disclosed
US-4061756-A Methods for treating cardiovascular disorders PARKE, DAVIS & COMPANY (US) 1977-12-06 US disclosed
US-4061756-A Methods for treating cardiovascular disorders PARKE, DAVIS & COMPANY (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007660-A1 TREATMENT AND PREVENTION OF SLEEP DISORDERS CRY1, PER2, SLC6A1 LMNA 2057/4885TDP1 852/4885CYP11B1 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.