Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11641651 | 0.89 | TDP1 (0.58) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| Sulfuric Acid SCHEMBL9644820 | 0.89 | TDP1 (0.58) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL29500180 | 0.88 | LMNA (0.72) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL78141 | 0.88 | LMNA (0.72) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL27968872 | 0.86 | LMNA (0.69) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| Hydrochloric Acid SCHEMBL9386460 | 0.86 | LMNA (0.69) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| Bromide SCHEMBL9391382 | 0.86 | LMNA (0.69) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL2845658 | 0.86 | LMNA (0.55) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9387464 | 0.86 | TDP1 (0.55) | TDP1LMNACYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6512870 | 0.82 | LTA4H (0.50) | TDP1LMNACYP19A1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040112-A1 | COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY | OXAGEN LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |