Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731705 | 0.92 | HTR2B (0.61) | BCHEACHELMNAOPRK1USP2 | |
| SCHEMBL14242762 | 0.85 | ACHE (0.52) | BCHEACHELMNAOPRK1USP2 | |
| SCHEMBL5787250 | 0.81 | HRH3 (0.56) | ACHELMNAOPRK1USP2ALDH1A1 | |
| SCHEMBL5787247 | 0.81 | HRH3 (0.56) | ACHELMNAOPRK1USP2ALDH1A1 | |
| SCHEMBL29285937 | 0.81 | OPRK1 (0.50) | BCHEACHELMNAOPRK1DRD2 | |
| SCHEMBL7531162 | 0.79 | LMNA (0.53) | LMNAALDH1A1HTR2B | |
| SCHEMBL26862272 | 0.79 | LMNA (0.60) | LMNAUSP2ALDH1A1HTR2B | |
| SCHEMBL21361595 | 0.79 | LMNA (0.61) | LMNAUSP2HTR2B | |
| SCHEMBL13810503 | 0.79 | LMNA (0.61) | LMNAUSP2ALDH1A1NPSR1HTR2B | |
| SCHEMBL15007091 | 0.78 | ACHE (0.52) | BCHEACHELMNADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101827852-B | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INT | 2014-07-30 | — | — | CN | disclosed |