Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21786279 | 0.78 | — | — | |
| SCHEMBL3801209 | 0.72 | HTR2A (0.42) | — | |
| SCHEMBL22898199 | 0.67 | CYP19A1 (0.36) | — | |
| SCHEMBL19074698 | 0.67 | AOC1 (0.30) | — | |
| SCHEMBL21547708 | 0.66 | SIGMAR1 (0.31) | — | |
| SCHEMBL28713089 | 0.63 | — | — | |
| SCHEMBL20470466 | 0.63 | SIGMAR1 (0.33) | — | |
| SCHEMBL20825128 | 0.63 | — | — | |
| SCHEMBL19444885 | 0.63 | — | — | |
| SCHEMBL28940071 | 0.63 | CHRNB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827101-A | New bicyclic dihydroquinoline-2-one derivatives | HOFFMANN LA ROCHE | 2014-05-28 | — | — | CN | disclosed |