Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31325165 | 1.00 | THRB (0.38) | THRBTDP1KIF11HSD11B1NPC1L1 | |
| SCHEMBL27860442 | 0.83 | KIF11 (0.35) | KIF11HSD11B1LMNATSHRMAPK1 | |
| SCHEMBL27860376 | 0.79 | KIF11 (0.35) | KIF11HSD11B1 | |
| SCHEMBL28032107 | 0.78 | THRB (0.44) | THRBTDP1KIF11HSD11B1NPC1L1 | |
| SCHEMBL2410771 | 0.77 | ALDH1A1 (0.36) | THRBTDP1LMNATSHRMAPK1 | |
| SCHEMBL6055589 | 0.76 | THRB (0.41) | THRBTDP1KIF11HSD11B1AKR1C1 | |
| SCHEMBL1500123 | 0.75 | MAPT (0.45) | TDP1TSHRMAPK1 | |
| SCHEMBL5488544 | 0.74 | TDP1 (0.36) | THRBTDP1KIF11HSD11B1AKR1C1 | |
| SCHEMBL14232376 | 0.73 | CCKAR (0.39) | THRBTDP1KIF11HSD11B1AKR1C1 | |
| SCHEMBL2408108 | 0.72 | KIF11 (0.38) | THRBTDP1KIF11AKR1C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036878-B | Large-flux anti-pollution reverse osmosis membrane, preparation method and application thereof | 万华化学集团股份有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-116036878-A | Large-flux anti-pollution reverse osmosis membrane, preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116036878-B | Large-flux anti-pollution reverse osmosis membrane, preparation method and application thereof | 万华化学集团股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119053336-A | Compositions and methods for treating autoimmune disorders | 密执安大学评议会 | 2024-11-29 | — | — | CN | disclosed |
| CN-118019768-A | Targeted delivery of therapeutic enzymes | 吉尼瑞姆股份公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116036878-A | Large-flux anti-pollution reverse osmosis membrane, preparation method and application thereof | 万华化学集团股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-114302741-A | Compositions and methods for treating autoimmune disorders | 密执安大学评议会 | 2022-04-08 | — | — | CN | disclosed |
| CN-104072486-A | BI-1H-BENZIMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO | 2014-10-01 | — | — | CN | disclosed |
| CN-102177141-B | bis-1H-benzimidazoles as hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | disclosed |